*Gil Gerard as Capt. William "Buck" Rogers
- Erin Gray as Col. Wilma Deering
- Tim O'Connor as Dr. Elias Huer
- Pamela Hensley as Princess Ardala
- Kelley Miles as Chandar
- Donald Petrie as Kodus
- Sid Haig as Spirot
- Michael Ansara as Kane
- Julie Newmar as Zarina
- Vera Miles as Tora
- Sam Jaffe as The Keeper
- Felix Silla as Twiki
- Mel Blanc as Voice of Twiki
- Tony Carroll as Pantherman
- Brent Davis as Goneril
- Eric Server as Voice of Dr. Theopolis
- Larry Ward as First Council Member
- Don Maxwell as Draconian Soldier
- Gary Adler as First Security Guard
- William Conrad as Voice of Narrator (uncredited)
- Kelli Lessie as Council Member (uncredited)
- Wesley Pfenning as Elana (uncredited)